The 4th generation folate for adults uses (6S)-5-methyltetrahydrofolic acid glucosamine salt as the main component, and adds ingredients beneficial for cardiovascular system, gastrointestinal tract, such as psylliumseedhusk, betaine, vitamin B6, vitamin B12, etc., taking methylation to synergy with desulphurization to achieve dual effects for rapid reducing HCY. When paired with CELFULL T-turnG, the efficacy can be doubled.